Recent publications by the FUNCFOOD participants

The  FUNCFOOD project has, so far, resulted in the following scientific publications:


1. Combating age realted diseases. Jenssen, D. Public Service Review EU, issue 20.

2. Structural requirements for mutation formation from polycyclic aromatic hydrocarbon dihydrodiol epoxides in their interaction with food chemopreventive compounds. Lagerqvist A, Håkansson D, Frank H, Seidel A and Jenssen D., Food Chem Toxicol. 2011.

3. Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice. Peters V, Schmitt CP, Zschocke J, Gross ML, Brismar K, Forsberg E., Amino Acids. 2011.

4. Inhibition of aldose reductase and sorbitiol accumulation by dietary rutin. Reddy, GB., Muthenna, P., Akileshwari, C., Saraswat, M., and Petrash, J.M., Curr Sci 2011.

5. Inhibition of advanced glycation end product formation on eye lens protein by rutin. Muthenna, M. Saraswat, C. Akileshwari and Reddy, GB., Br J Nutr. 2011.


6. Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis. Anitha, P., Priyadarsini, R.V., Kavitha, K., Thiyagarajan, P., Nagini, S.Eur J Nutr, 2011.


7. Cancer chemoprevention by dietary phytochemicals: promises and pitfalls. Priyadarsini RV, Nagini S. Current Pharmaceutical Biotechnology, 2012.


8. Ellagic acid, a new antiglycating agent: its inhibition of Nε-(carboxymethyl)lysine. Muthenna, P., Akileshwari, C., and Reddy, GB., Biochem. J. 2012.

9. Coenzyme Q10 prevents GDP-sensitive kidney mitochondria uncoupling, glomerular hyperfiltration and proteinuria in type-2 diabetic db/db mice. Friederich Persson M, Catrina SB, Dallner G, Hansell P, Brismar K, Palm F. Diabetologia, 2012.

10.The Isolation and Characterization of b-Glucogallin as a Novel Aldose Reductase Inhibitor from Emblica officinalis  Muthenna, P.,  Ponder, J.,  Suryanarayana, P., Reddy, GB., Petrash, J. M., LaBarbera, D. V.  PloS One, 2012.


11. Dietary chlorophyllin inhibits the canonical NF-κB signaling pathway and induces intrinsic apoptosis in a hamster model of oral oncogenesis.

Thiyagarajan, P., Senthil, Murugan R., Kavitha, K., Anitha, P., Prathiba, D., Nagini, S. Food and Chemical Toxicology, 2012.


12. Gene expression signature of DMBA-induced hamster buccal pouch carcinomas: modulation by chlorophyllin and ellagic acid.

Vidya Priyadarsini, R., Kumar, N., Khan, I., Thiyagarajan, P., Kondaiah, P., Nagini, S. PloS one, 2012.


13. Protective effect of ellagic acid (EA) on N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) induced micronuclei in mammalian cells in vitro and in vivo assays. Berni, A., Rosaria Grossi, M., Pepe, G., Filippi, S., Muthukumar, S., Papeschi, C., Natarajan, A.T., and Palitti, F., Mutat Res., 2012.


14. Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts. Nastasijevic, B., Lazarevic-Pasti, T., Dimitrijevic-Brankovic, S, Pastic, I., Vujacic, A., Joksic, G., Vasic, V. JBPA, 2012.


15. Tomato juice intake suppressed serum concentration of 8-oxodG after extensive physical activity. Harms-Ringdahl, M., Jenssen, D., Haghdoost, S. Nutrition Journal, 2012.


16. Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes Ansurudeen, I., Gupta Sunkari, V., Grunler,J.,  Peters, V., Schmitt, C.P., Sergiu-Bogdan, C., Brismar, K., Alcantara Forsberg, E. Amino Acids, 2012.


17. A comparative study of the anticlastogenic effects of chlorophillin on N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) or 7,12-dimethylbenz (α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo.

Grossi MR, Berni A, Pepe G, Filippi S, Mosesso P, Shivnani AA, Papeschi C, Natarajan AT, Palitti F. Toxicology Letters, 2012.

18. Inhibition of aldose reductase by Gentiana lutea extracts.

Akileshwari C, Muthenna P, Nastasijević B, Joksić G, Petrash JM, Reddy GB. Exp. Diabetes res. 2012